ANNA 2016

Advances in Noncanonical Nucleic Acids

Program

Wednesday, May 18, 2016.

Venue: National Institute of Chemistry, Hajdrihova 19, Ljubljana, Slovenija

Map

15:30 – 15:45

Registration and welcome

15:45 – 16:00

Opening remarks: Janez Plavec Head of NMR Centre,

Gregor Anderluh Director of NIC

Chair: Peter Podbevšek

16:00 – 16:30

Jyoti Chattopadhyaya: Does the Nucleobase-sequence in a given RNA or DNA molecule actually signify a chemical signal? Does the Sequence itself, per se, represent a chemical entity, or just an agglomeration of monomeric units for defined self-assembly by H-bonding?

16:30 – 17:00

Naoki Sugimoto: Regulation of gene expressions using the formation of noncanonical structures of nucleic acids

17:00 – 17:30

Marie-Paule Teulade-Fichou: Quadruplex interactive compounds: from in vitro targeting to in vivo probing

17:30 – 18:00

Zhen Xi: Gene Nanovector through Branch-PCR

18:00 – 18:30

Barbara Nawrot: Why Nature uses non-canonical base pairing for codonanticodon interactions

19:00

Welcome reception

Thursday, May 19, 2016

Venue: Jable Castle, Grajska cesta 1, Mengeš, Slovenija

Map

8:30

Bus transfer from hotels to the venue

Chair: Marie-Paule Teulade-Fichou

9:30 – 10:00

Luigi Xodo: Molecular strategies to inhibit the ras genes in cancer cells

10:00 – 10:30

Lukas Trantirek: The G-hairpin DNA

10:30 – 10:50

Lea Spindler: Long G-quadruplex nanowires formed by G:C linkages

10:50 – 11:20

Coffee break

11:20 – 11:50

Jean-Louis Mergny: Quadruplexes are everywhere

11:50 – 12:10

Tamaki Endoh: Co-transcriptional G-quadruplex formation affected by mutually exclusive hairpin

12:10 – 12:30

Jure Lah: Thermodynamic description of structural transitions of a human telomere DNA fragment

12:30 – 14:30

Lunch & poster session

Chair: Luigi Xodo

14:30 – 15:00

Mateus Webba da Silva: G-quadruplex topologies of three loops

15:00 – 15:30

Viktor Viglasky: The Biological Role and Occurrence of G-quadruplexes in Viruses

15:30 – 15:50

Marina Juribašić Kulcsar: Stabilizing interactions in a long-loop Gquadruplex formed within promoters of Plasmodium falciparum B var genes

15:50 – 16:10

Shuntaro Takahashi: Pressure control of the formation of G-quadruplex and i-motif DNA

16:10 – 16:40

Coffee break

Chair: Jean-Louis Mergny

16:40 – 17:10

Antonio Randazzo: Developing of new selective DNA G-quadruplex ligands

17:10 – 17:40

Gilmar Salgado: NMR Structure and Ligand Binding of a new G-Quadruplex Forming Sequence within the KRAS Promoter Region

17:40 – 18:00

Primož Šket: Guanine-rich DNA oligonucleotides: formation of Gquadruplexes

18:00

Closing remarks - Janez Plavec

18:30

Banquet Dinner

Friday, May 2016

9:00

Individual discussions /departure