A great publication in Nature Communications

A new 3D structure formed by DNA sequences with GGGAGCG repeats found in the regulatory region of the PLEKHG3 gene was determined. Such a G-rich sequence was expected to form G-quadruplexes. For the first time a G-rich sequence was demonstrated to adopt a four-stranded architecture distinct from G-quadruplexes. The fold is stabilized not only by the presence of Na⁺, K⁺ and NH₄⁺ but also Li⁺ ions. The new fold expands the known repertoire of DNA structures.

For more information read the full paper at Nature Communications.